Indian Journal of Respiratory Care

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VOLUME 10 , ISSUE S1 ( April, 2021 ) > List of Articles

REVIEW ARTICLE

Pediatric COVID: How is it Different From Adults?

Rakhee Goyal, Rohan Sharma

Keywords : COVID-19, multisystem inflammatory syndrome, pediatric, spreaders

Citation Information :

DOI: 10.4103/ijrc.ijrc_41_21

License: CC BY-NC-SA 4.0

Published Online: 06-12-2022

Copyright Statement:  Copyright © 2021; Indian Journal of Respiratory Care.


Abstract

COVID 19 pandemic has affected the world for more than one year now. It has had impact on children as well, but the numbers have been fewer than adults, with lesser morbidity. Children have been commonly asymptomatic and are suspected to be the spreaders to the more susceptible part of the community. Nasopharyngeal swab testing is difficult and challenging in smaller children, and therefore their results should be interpreted with caution. Multisystem involvement has been seen in some children who required ICU admission. Most centers treated these cases as a multisystem inflammatory syndrome and used vasoactive agents for support. Overall, children showed lower morbidity and mortality all over the world.


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  1. World Health Organisation. Countries Where COVID-19 Has Spread. Available from: https://www.worldometers.info/coronavirus/countrieswhere- coronavirus-has-spread. [Last accessed on 2021 Mar 01].
  2. American Academy of Pediatrics. Children and COVID-19: State Level Data Report. Available from: https://services.aap.org/en/pages/2019- novel-coronavirus-covid-19-infections/children-and-covid-19-statelevel- data-report. [Last accessed on 2021 Feb 25].
  3. Centers for Disease Control and Prevention. Available from: https://www.cdc.gov/coronavirus/2019-ncov/symptoms-testing/testing. html. [Last accessedon 2021 Feb 25].
  4. Kapoor MC. Reducing the viral load while securing the airway. J Anaesthesiol Clin Pharmacol 2020;36:S147-8.
  5. Heald-Sargent T, Muller WJ, Zheng X, Rippe J, Patel AB, Kociolek LK. Age-related differences in nasopharyngeal severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) levels in patients with mild to moderate coronavirus disease 2019 (COVID-19). JAMA Pediatr 2020;174:902-3.
  6. Chen J. Pathogenicity and transmissibility of 2019-nCoV - A quick overview and comparison with other emerging viruses. Microbes Infect 2020;22:69-71.
  7. Gu J, Han B, Wang J. COVID-19: Gastrointestinal manifestations and potential fecal-oral transmission. Gastroenterology 2020;158:1518-9.
  8. Hindustan Times. 54 Students Test COVID-19 Positive at School in Haryana's Karnal. Available from: https://www.hindustantimes.com/india-news/54-students-test-covid-19-positive-at-school-in-haryana-skarnal-101614687017066.html. [Last accessed on 2021 Mar 05].
  9. The Hindu. In Kerala, 150 Students of a School Test Positive. Available from: https://www.thehindu.com/news/national/kerala/150-students-ofa- school-test-positive. [Last accessed on 2021 Mar 05].
  10. Foster CE, Moulton EA, Munoz FM, Hulten KG, Versalovic J, Dunn J, et al. Coronavirus Disease 2019 in children cared for at texas children's hospital: Initial clinical characteristics and outcomes. J Pediatric Infect Dis Soc 2020;9:373-7.
  11. Shekerdemian LS, Mahmood NR, Wolfe KK, Riggs BJ, Ross CE, McKiernan CA, et al. Characteristics and outcomes of children with Coronavirus Disease 2019 (COVID-19) infection admitted to US and Canadian pediatric intensive care units. JAMA Pediatr 2020;174:868-73.
  12. Feldstein LR, Rose EB, Horwitz SM, Collins JP, Newhams MM, Son MB, et al. Multisystem inflammatory syndrome in U.S. children and adolescents. N Engl J Med 2020;383:334-46.
  13. Jones VG, Mills M, Suarez D, Hogan CA, Yeh D, Segal JB, et al. COVID-19 and Kawasaki disease: Novel virus and novel case. Hosp Pediatr 2020;10:537-40.
  14. Riphagen S, Gomez X, Gonzalez-Martinez C, Wilkinson N, Theocharis P. Hyperinflammatory shock in children during COVID-19 pandemic. Lancet 2020;395:1607-8.
  15. Verdoni L, Mazza A, Gervasoni A, Martelli L, Ruggeri M, Ciuffreda M, et al. An outbreak of severe Kawasaki-like disease at the Italian epicentre of the SARS-CoV-2 epidemic: An observational cohort study. Lancet 2020;395:1771-8.
  16. WHO. Multisystem Inflammatory Syndrome in Children and Adolescents with COVID-19. Available from: https://www.who.int/publications/i/item/multisystem-inflammatory-syndrome-in-childrenand- adolescents-with-covid-19. [Last accessed on 2020 Sep 10].
  17. The Royal College of Paediatrics and Child Health. Guidance - Paediatric Multisystem Inflammatory Syndrome Temporally Associated with COVID-19 (PIMS); 2020. Available from: https://www.rcpch.ac.uk/resources/guidance-paediatric-multisystem-inflammatory-syndrometemporally- associated-covid-19-pims. [Last accessed on 2021 Feb 25].
  18. Qiu H, Wu J, Hong L, Luo Y, Song Q, Chen D. Clinical and epidemiological features of 36 children with coronavirus disease 2019 (COVID-19) in Zhejiang, China: An observational cohort study. Lancet Infect Dis 2020;20:689-96.
  19. Chan JF, Yuan S, Kok KH, To KK, Chu H, Yang J, et al. A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: A study of a family cluster. Lancet 2020;395:514-23.
  20. Huang C, Wang Y, Li X, Ren L, Zhao J, Hu Y, et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet 2020;395:497-506.
  21. Dong L, Tian J, He S, Zhu C, Wang J, Liu C, et al. Possible vertical transmission of SARS-CoV-2 from an infected mother to her newborn. JAMA 2020;323:1846-8.
  22. Chen H, Guo J, Wang C, Luo F, Yu X, Zhang W, et al. Clinical characteristics and intrauterine vertical transmission potential of COVID-19 infection in nine pregnant women: A retrospective review of medical records. Lancet 2020;395:809-15.
  23. Zhang L, Jiang Y, Wei M, Cheng BH, Zhou XC, Li J, et al. Analysis of the pregnancy outcomes in pregnant women with COVID-19 in Hubei Province. Zhonghua Fu Chan Ke Za Zhi 2020;55:166-71.
  24. Chen S, Huang B, Luo DJ, Li X, Yang F, Zhao Y, et al. Pregnancy with new coronavirus infection: clinical characteristics and placental pathological analysis of three cases. Zhonghua Bing Li Xue Za Zhi 2020;49:418-23.
  25. Rasmussen SA, Smulian JC, Lednicky JA, Wen TS, Jamieson DJ. Coronavirus Disease 2019 (COVID-19) and pregnancy: What obstetricians need to know. Am J Obstet Gynecol 2020;222:415-26.
  26. Mimouni F, Lakshminrusimha S, Pearlman SA, Raju T, Gallagher PG, Mendlovic J. Perinatal aspects on the covid-19 pandemic: A practical resource for perinatal-neonatal specialists. J Perinatol 2020;40:820-6.
  27. Peng PW, Wong DT, Bevan D, Gardam M. Infection control and anesthesia: Lessons learned from the Toronto SARS outbreak. Can J Anaesth 2003;50:989-97.
  28. Scales DC, Green K, Chan AK, Poutanen SM, Foster D, Nowak K, et al. Illness in intensive care staff after brief exposure to severe acute respiratory syndrome. Emerg Infect Dis 2003;9:1205-10.
  29. Loeb M, McGeer A, Henry B, Ofner M, Rose D, Hlywka T, et al. SARS among critical care nurses, Toronto. Emerg Infect Dis 2004;10:251-5.
  30. Kamming D, Gardam M, Chung FI. Anaesthesia and SARS. Br J Anaesth 2003;90:715-8.
  31. UNICEF. Available from: https://data.unicef.org/resources/remotelearning- reachability-factsheet. [Last accessed on 2021 Mar 05].
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