Cryptogenic organizing pneumonia (COP) with sarcoidosis, as an overlap disease, occurs infrequently. We report a case of an elderly female, who was diagnosed as a case of COP based on radiological and histopathological evaluation. After the systemic steroid therapy, there occurred a significant fall in serum angiotensin-converting enzyme (SACE) levels, pointing toward the clinical diagnosis of sarcoidosis. This case raises the possibility of sarcoidosis as an etiology of COP in patients with a mixed spectrum of presentation.
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