Indian Journal of Respiratory Care

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VOLUME 12 , ISSUE 4 ( October-December, 2023 ) > List of Articles

Original Article

Hematologic Parameters and Their Limiting Values as Prognostic Factors in COVID-19

Bhargavi K Nagabhushan, Puneet Nagendra, Sandeepa HS, Supriya Sandeepa

Keywords : Coronavirus, Coronavirus disease 2019, Limiting values, Mortality, Neutrophil to lymphocyte ratio, Platelet to lymphocyte ratio

Citation Information : Nagabhushan BK, Nagendra P, HS S, Sandeepa S. Hematologic Parameters and Their Limiting Values as Prognostic Factors in COVID-19. Indian J Respir Care 2023; 12 (4):303-307.

DOI: 10.5005/jp-journals-11010-1080

License: CC BY-NC-SA 4.0

Published Online: 18-01-2024

Copyright Statement:  Copyright © 2023; The Author(s).


Introduction: The manifestations of coronavirus disease 2019 (COVID-19) are varied and range from asymptomatic to life-threatening cases requiring intensive care. Currently, an expeditious prediction of disease severity and outcomes in the early stages remains an unmet challenge. This study aims to critically examine the hematologic values predominantly, along with sociodemographic and clinical parameters, to identify their limiting values that can prognosticate the disease. Materials and methods: A cross-sectional retrospective study was conducted in a rural medical college hospital in Ramanagara, Karnataka. The necessary data of the inpatients were recorded from their respective case files available in the Medical Records Department (MRD). Results: Of the 442 COVID-19 cases, 402 cases were survivors, and 40 cases were nonsurvivors. A statistical significance (p-value of <0.001) was noted between these two categories for the following parameters in our study: oxygen saturation, total count, neutrophil count and lymphocyte count, neutrophil-to-lymphocyte ratio (NLR), and platelet-to-lymphocyte ratio (PLR). The limiting values that were derived had an increased risk of mortality with respect to these parameters: oxygen saturation (<86.5%), NLR (>4.5), and PLR (>270.50). Conclusion: Identification and implementation of these prognostic markers are of substantial value to the physicians who continue to be challenged by COVID-19, more so in countries with limited healthcare resources.

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