Aim and background: This study aimed to evaluate smartphone game application with the Buteyko breathing technique to improve pulmonary function in asthma patients. Airway constriction and inflammation are the hallmarks of asthma. It is the most prevalent chronic illness in both adults and children. Although there are many recent studies showing the effectiveness of various methods, the Buteyko method and game therapy applications may reduce medication needs and symptoms. Methods: This was a quasi-experimental study of pre- and posttrial type carried out with 30 children diagnosed with asthma. Based on the inclusion and exclusion criteria, they were chosen using a simple random sampling method and split into two groups. Subjects of group A received the Buteyko breathing technique, and subjects of group B received the Buteyko breathing technique along with an interventional digital breathing technique, for 15 minutes, 5 sessions per week for 4 weeks. The pre- and posttest were analyzed using the Asthma Control Test and the Becker Asthma Score. Results: On comparison, a significant difference in means at p ≤ 0.05 was observed in group B when comparing the Academic Competence Test (ACT) and Behavioral Assessment Scale (BAS) scores of groups A and B between pre- and posttests. Conclusion: The Buteyko breathing technique along with the Digital Interventional Breathing Technique is more effective in improving pulmonary function in asthma patients compared to the Buteyko breathing technique. The findings of this study pave the way for depicting the role of games in the treatment protocol, by improving the interaction of the patient and thereby improving pulmonary function. Clinical significance: The evaluation of digital solutions for asthma, including artificial intelligence (AI)-assisted breathing techniques and the Buteyko method, holds significant clinical relevance. These innovative approaches offer potential advancements in personalized asthma management by improving breathing efficiency and reducing reliance on medication. Digital interventional breathing techniques can provide real-time feedback and tailored exercises, while the Buteyko method emphasizes controlled breathing to reduce symptoms. Together, these technologies promise to enhance patient outcomes, increase adherence to treatment protocols, and ultimately improve the quality of life for individuals with asthma.