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VOLUME 8 , ISSUE 1 ( January-June, 2019 ) > List of Articles

Original Article

Tuberculosis in Larynx

Sunil Grover, Keerat Kaur Sibia, Vanita Sarin

Keywords : Bronchoscopy, hoarseness, laryngeal tuberculosis, odynophagia, vocal cords

Citation Information : Grover S, Sibia KK, Sarin V. Tuberculosis in Larynx. Indian J Respir Care 2019; 8 (1):51-56.

DOI: 10.4103/ijrc.ijrc_14_18

License: CC BY-NC-SA 4.0

Published Online: 05-12-2022

Copyright Statement:  Copyright © 2019; Indian Journal of Respiratory Care.


Introduction: Laryngeal tuberculosis (TB) has shown increase in incidence in recent years and the increase in immunosuppressive conditions has altered the clinical profile of the disease. The aim of this study was to evaluate the changing trends of laryngeal TB and to highlight its site of involvement, type of lesion, and degree of involvement. Patients and Methods: This prospective study included 54 patients with a diagnosis of laryngeal TB. All patients were evaluated in terms of their age, chief complaints, lesions, and site of involvement on flexible fiber-optic bronchoscopy, and they also underwent a variety of laboratory investigations as indicated. Results: The study showed that true vocal cords + false cords + epiglottis were involved in 48.1% (n = 26), arytenoids + interarytenoid + posterior part of true cords in 24.1% (n = 13), true cords + false cords + arytenoids + interarytenoid in 18.5% (n = 10), true vocal cords alone in 5.5% (n = 3), interarytenoid in 1.8% (n = 1), and interarytenoid + arytenoid involvement was seen in 1.8% (n = 1) of patients. These lesions were categorized into four different appearances as follows: granulomatous lesions in 50% (n = 27), ulcerative lesions in 27.7% (n = 15), hyperemia and hypertrophic in 16.7% (n = 9), and papillomatous mass in 5.6% (n = 3) based on fiber-optic bronchoscopy. Conclusion: In this study, the disease was most rampant in the age group of 31-60 years, with a predilection seen in low socioeconomic groups, rural groups and in individuals addicted to smoling and alcoholism. Hoarseness and odynophagia are the major symptoms. Multiple subsites are involved, and the lesions show a predilection for the anterior part of the vocal cord.

  1. World Health Organization. “Fact sheet No. 104: “Tuberculosis”. World Health Organization; 2007.
  2. Kandiloros DC, Nikolopoulos TP, Ferekidis EA, Tsangaroulakis A, Yiotakis JE, Davilis D, et al. Laryngeal tuberculosis at the end of the 20th century. J Laryngol Otol 1997;111:619-21.
  3. Shin JE, Nam SY, Yoo SJ, Kim SY. Changing trends in clinical manifestations of laryngeal tuberculosis. Laryngoscope 2000;110:1950-3.
  4. Yencha MW, Linfesty R, Blackmon A. Laryngeal tuberculosis. Am J Otolaryngol 2000;21:122-6.
  5. Levenson MJ, Ingerman M, Grimes C, Robbett WF. Laryngeal tuberculosis: Review of twenty cases. Laryngoscope 1984;94:1094-7.
  6. Rizzo PB, Da Mosto MC, Clari M, Scotton PG, Vaglia A, Marchiori C, et al. Laryngeal tuberculosis: An often forgotten diagnosis. Int J Infect Dis 2003;7:129-31.
  7. Ling L, Zhou SH, Wang SQ. Changing trends in the clinical features of laryngeal tuberculosis: A report of 19 cases. Int J Infect Dis 2010;14:e230-5.
  8. Lim JY, Kim KM, Choi EC, Kim YH, Kim HS, Choi HS, et al. Current clinical propensity of laryngeal tuberculosis: Review of 60 cases. Eur Arch Otorhinolaryngol 2006;263:838-42.
  9. Fortún J, Sierra C, Raboso E, Pérez C, Plaza G, Navas E, et al. Tuberculosis of the otorhinolaryngologic region: Laryngeal and extra-laryngeal forms. Enferm Infecc Microbiol Clin 1996;14:352-6.
  10. Bailey CM, Windle-Taylor PC. Tuberculous laryngitis: A series of 37 patients. Laryngoscope 1981;91:93-100.
  11. Thaller SR, Gross JR, Pilch BZ, Goodman ML. Laryngeal tuberculosis as manifested in the decades 1963-1983. Laryngoscope 1987;97:848-50.
  12. Wang CC, Lin CC, Wang CP, Liu SA, Jiang RS. Laryngeal tuberculosis: A review of 26 cases. Otolaryngol Head Neck Surg 2007;137:582-8.
  13. Nishiike S, Irifune M, Doi K, Sawada T, Kubo T. Laryngeal tuberculosis: A report of 15 cases. Ann Otol Rhinol Laryngol 2002;111:916-8.
  14. Rupa V, Bhanu TS. Laryngeal tuberculosis in the eighties - An Indian experience. J Laryngol Otol 1989;103:864-8.
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