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VOLUME 9 , ISSUE 2 ( July-December, 2020 ) > List of Articles

Original Article

Desaturation on 6-Min Walk Test: A Test with High Negative Predictive Value to Rule Out Pulmonary Hypertension in Interstitial Lung Diseases

Vishwas Gupta, Swapnil Manaji Thorve, Pralhad Prabhakar Prabhudesai

Keywords : 6-min walk test, desaturation, interstitial lung diseases, pulmonary hypertension

Citation Information : Gupta V, Thorve SM, Prabhudesai PP. Desaturation on 6-Min Walk Test: A Test with High Negative Predictive Value to Rule Out Pulmonary Hypertension in Interstitial Lung Diseases. Indian J Respir Care 2020; 9 (2):196-198.

DOI: 10.4103/ijrc.ijrc_63_19

License: CC BY-NC-SA 4.0

Published Online: 08-12-2022

Copyright Statement:  Copyright © 2020; Indian Journal of Respiratory Care.


Introduction: Pulmonary hypertension (PH) is one of the major complications of interstitial lung diseases (ILDs) that contributes to increased morbidity and mortality. Predicting and promptly diagnosing PH may improve the outcome in these patients. We evaluated the utility of 6-min walk test (6MWT) to predict PH earlier in the course of ILDs. Patients and Methods: A total of 113 patients diagnosed with ILD as per standard investigation protocols were included in this observational study. Patients were evaluated with 6MWT, pulmonary function tests, and two-dimensional echocardiogram. Patients having mean pulmonary arterial pressure >25 mmHg were labeled as PH, and 4% drop from pretest oxygen saturation was considered as significant desaturation. Results: It was observed that 40% of patients with desaturation on 6MWT had PH. None of the patients without significant desaturation had PH. Conclusion: Desaturation on 6MWT is not an early predictor of PH, which is one of the major complications of ILDs. However, it has a high negative predictive value in the prediction of PH in patients with ILD.

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