• Users Online: 190
  • Print this page
  • Email this page

 Table of Contents  
Year : 2020  |  Volume : 9  |  Issue : 2  |  Page : 243-244

Beware from inadvertent fitting of the disposable syringe

1 Department of Critical Care Medicine, Rajendra Institute of Medical Sciences, Ranchi, Jharkhand, India
2 Department of Intensive Care Medicine, Rajendra Institute of Medical Sciences, Ranchi, Jharkhand, India

Date of Submission18-Mar-2020
Date of Acceptance02-Apr-2020
Date of Web Publication19-Jun-2020

Correspondence Address:
Dr. Jay Prakash
C/O R. P. Sinha, HI-166, Harmu Housing Colony, Ranchi - 834 002, Jharkhand
Login to access the Email id

Source of Support: None, Conflict of Interest: None

DOI: 10.4103/ijrc.ijrc_23_20

Rights and Permissions

How to cite this article:
Prakash J, Khan MS, Kharwar RK, Mishra A. Beware from inadvertent fitting of the disposable syringe. Indian J Respir Care 2020;9:243-4

How to cite this URL:
Prakash J, Khan MS, Kharwar RK, Mishra A. Beware from inadvertent fitting of the disposable syringe. Indian J Respir Care [serial online] 2020 [cited 2022 Dec 5];9:243-4. Available from: http://www.ijrc.in/text.asp?2020/9/2/243/287302


Damage to the injection port of the central venous catheter (CVC) is rare. We encountered such a problem during utilization of a CVC. After an extensive literature search, we found an incidence with epidural catheter filter port with different brands of disposable 10-ml syringes,[1] but we did not find any case with CVC. A 56-year-old woman weighing 64 kg was admitted to our hospital with severe pneumonia and hypotension. She was on ventilator support because of acute respiratory failure and vasopressor support. A double-lumen 7 Fr. CVC (NewTech™ Medical Devices, New Delhi, India) was inserted in the right subclavian vein using a landmark technique to monitor central venous pressure and to administer medications.

In the initial 3 days, her blood pressure was maintained (≈130/80 mmHg) with vasopressor infusion. However, on the 4th day, she became hypotensive (<90/60 mmHg). The bedsheet was seen to have been stained reddish color below the right shoulder because of backflow. The blood was coming back slowly through one port. On close observation, a crack was found in one of the ports of the CVC, leading to spillage of blood [Figure 1]. We flushed it with normal saline. On enquiry about the possible cause of this incidence, we found that in our hospital, disposable syringes of different volumes and different brands are supplied. We also noticed that there was a slight difference in the nozzle diameter of these syringes [Figure 2], and we suspect that the use of a syringe with a slightly larger diameter might have led to the damage to the injection port of the CVC. We tend to speculate that an effort during flushing might have caused the damage and resulted in an outflow of medication. Unobserved, such spillage can cause inadequate drug delivery.
Figure 1: Cracked injection port of the central venous catheter

Click here to view
Figure 2: Different nozzle diameters of different volume of syringes of different brands

Click here to view

To maintain catheter patency and function, flushing of a CVC or vascular access devices (VADs) is a crucial intervention. By national and international guidelines, flushing is recommended in concurrence with the manufacturer's instructions for use to optimize VAD safety, function, and durability for all those patients who require short- or long-term intravenous therapy.[2] Flushing a VAD using the proper technique, at the right time, is much more than just injecting fluid into a catheter lumen.[3] It requires knowledge of flushing techniques and needle-free connectors by the healthcare professional providing hands-on care.[4] To eliminate inadvertent blood reflux, we may use prefilled syringes, but they are costlier than usual disposable syringes.

Prefilled syringe flush volumes are available in 3, 5, and 10 mL options for various VAD type, length, and size. The smaller volume prefilled syringes are produced in diameters and dimensions consistent with a 10-mL syringe barrel,[5] generating significantly less pressure[1] than standard 5 and 3 mL syringes. Flushing VADs incorrectly, by exerting high pressures with smaller syringes than the manufacturer's recommendations, suggests that it may contribute to catheter rupture, especially if resistance is met on flushing the device.[6],[7] On this unusual event with lack of regulatory standardization, we would like to suggest that there should be a gentle application of syringe in the injection port of the CVC. We also suggest that one should look for any leakage during drug administration. If spillage is present, we should suture or clamp the damaged injection port of the CVC. It may be better to connect three-way stopcocks to each port of CVC. Even if damage occurs, it would occur to one of the three-way stopcocks and avoid damage to CVC ports.

Declaration of patient consent

The authors certify that they have obtained all appropriate patient consent forms. In the form the patient has given her consent for her images and other clinical information to be reported in the journal. The patient understand that her names and initials will not be published and due efforts will be made to conceal her identity, but anonymity cannot be guaranteed.

Financial support and sponsorship


Conflicts of interest

There are no conflicts of interest.

  References Top

Kumar N, Kumar A, Dubey PK. Crack in the epidural catheter filter port. Saudi J Anaesth 2018;12:646-7.  Back to cited text no. 1
Gorski L, Hadaway L, Hagle M, McGoldrick M, Orr M, Doellman D. Infusion therapy standards of practice. J Infus Ther 2016;39:1S.  Back to cited text no. 2
Hadaway L. Flushing vascular access catheters: Risks for infection transmission. Infect Control Res 2009;4:1-7.  Back to cited text no. 3
Moureau N. Safe patient care when using vascular access devices. Br J Nurs 2013;22:S14, S16.  Back to cited text no. 4
Keogh S, Flynn J, Marsh N, Mihala G, Davies K, Rickard C. Varied flushing frequency and volume to prevent peripheral intravenous catheter failure: A pilot, factorial randomised controlled trial in adult medical-surgical hospital patients. Trials 2016;17:348.  Back to cited text no. 5
Bishop L, Dougherty L, Bodenham A, Mansi J, Crowe P, Kibbler C, et al. Guidelines on the insertion and management of central venous access devices in adults. Int J Lab Hematol 2007;29:261-78.  Back to cited text no. 6
Pittiruti M, Hamilton H, Biffi R, MacFie J, Pertkiewicz M; ESPEN. ESPEN Guidelines on Parenteral Nutrition: Central venous catheters (access, care, diagnosis and therapy of complications). Clin Nutr 2009;28:365-77.  Back to cited text no. 7


  [Figure 1], [Figure 2]


Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
Access Statistics
Email Alert *
Add to My List *
* Registration required (free)

  In this article
Article Figures

 Article Access Statistics
    PDF Downloaded167    
    Comments [Add]    

Recommend this journal